526互联

Loss-of-function

LOEUF (the loss-of-function observed/expected upper bound fraction) 和 pLI (probability of being Loss-of-function Intoleran)

LOEUF (the loss-of-function observed/expected upper bound fraction): LOEUF is a conservative estimate of evolutionary selection against disease-causin ......
function loss-of-function Loss-of-function probability Intoleran
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